What is the Elephantiasis Disease?

Elephantiasis refers to a parasitic contamination that causes excessive swelling inside the arms and legs.

The sickness is resulting from the filarial worm, which is transmitted form human to human through the woman mosquito while it takes a blood meal. The parasite grows into an person bug that lives within the lymphatic device of people.

Elephantiasis is generally characterised via a thickening of the pores and skin and subcutaneous tissue that offers rise to the grossly enlarged and swollen limbs that earn the situation its call. The situation is also referred to as lymphatic filariasis.

Epidemiology or incidence of the circumstance

The condition presently affects over 120 million humans, with 40 million tormented by a extreme shape of the sickness. Elephantiasis is most not unusual among populations from India; an Indian individual is affected in a single third of all cases. Another 1/3 of instances involve humans from Africa and the the rest are from South Asia, the Americas and the Pacific. The contamination is most widely recognized in tropical and subtropical regions.




Causes

Examples of nematode parasites that motive lymphatic filariasis consists of Wuchereria bancrofti, Brugia malayi, and Brugia timori. The larvae (microfilariae) of the parasite are taken up by means of the mosquito when it feeds. When the larvae reach the 1/3 stage of improvement, they're brought to a brand new host, who then develops the contamination.

Diagnosis and remedy

The general check for detecting the infection is microscopic exam of a blood smear for presence of the microfilariae. The blood must be sampled at night time due to the fact the microfilariae circulate thru the blood nocturnally.

The fundamental medicinal drug used to treat this circumstance is diethylcarbamazine or DEC, which kills the microfilariae as well as a few adult worms. The medicinal drug is generally well tolerated however aspect results consist of dizziness, fever and aching muscle tissues.

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